A targeted B-vitamin formula used when stress feels physically draining. Emphasizes nutrients commonly associated with adrenal hormone production rather than broad daily B-complex support.*
NuMedica Corti-B Plex™ is a targeted B-vitamin formula used when everyday stress begins to feel more physically demanding. Rather than providing a full B-complex, it emphasizes nutrients commonly associated with adrenal hormone production and sustained energy needs.
This formula is typically considered by adults who feel that general B-vitamin support is no longer enough to keep up with ongoing mental or physical pressure.
Corti-B Plex is often used in situations such as:
In these situations, support is often narrowed toward nutrients involved in adrenal hormone production rather than broad daily coverage.
Corti-B Plex is not intended to replace medical care, address diagnosed adrenal disorders, or compensate for chronic sleep loss, inadequate nutrition, or unmanaged stress. It is also not designed to serve as a comprehensive daily multinutrient foundation.
This formula is best understood as a targeted option used when general B-vitamin support no longer feels sufficient on its own.
During prolonged stress, the body may place greater demand on certain nutrients involved in energy metabolism and hormone synthesis. In those situations, evenly distributed B-vitamin support may feel less effective than a more focused approach.
Corti-B Plex reflects this shift by emphasizing pantothenic acid and vitamin B6 rather than spreading support across the entire B-vitamin spectrum.
Sustained physical or mental stress can increase the body's reliance on nutrients associated with adrenal hormone production and cellular energy processes. Corti-B Plex includes vitamin C, bioflavonoids, and acetyl-L-carnitine alongside targeted B vitamins to support this pattern of demand.
This approach avoids stimulants and herbal adaptogens, making it suitable for individuals who prefer a nutrient-only strategy.
Several NuMedica formulas address stress-related nutrient needs. The comparison below highlights the options most commonly considered at this stage.
| B-Replete | Corti-B Plex | AdrenaMed | |
|---|---|---|---|
| Form | B-complex | Targeted B vitamins | B vitamins with adaptogenic herbs |
| Primary active per serving | Full B-vitamin spectrum | Pantothenic acid, vitamin B6 | Adaptogens plus adrenal-support nutrients |
| Release style | Standard oral capsules | Standard oral capsules | Standard oral capsules |
| Adjustability | Daily baseline | Used during higher demand | Used during sustained or complex stress |
| Taste / format | Capsules | Capsules | Capsules |
| Best for | Everyday energy and stress tolerance | Physically draining stress patterns | Ongoing adrenal stress requiring herbal support |
Some individuals return to a general B-complex once stress levels stabilize. Others move toward adrenal formulas that include adaptogenic herbs when stress patterns become more persistent or complex.
Corti-B Plex is most often used as a middle step between broad daily support and more involved adrenal strategies.
NuMedica Corti-B Plex™ is designed to support periods of increased adrenal demand rather than serve as a permanent daily foundation. It fits best within a long-term routine that also includes adequate food intake, rest, movement, and realistic stress management.
This formula provides a more focused approach while keeping supplementation straightforward and restrained.
Size: 120 Vegetable Capsules
Serving Size: 2 Capsules
Servings Per Container: 60
Directions: Take two capsules 1-2 times per day or as directed by your healthcare practitioner.
| Nutrient/Ingredient | Amount | % Daily ValueDV 1 |
|---|---|---|
|
Vitamin C (as magnesium ascorbate)
Vitamin C
Vitamin C is a powerful antioxidant that supports immune health, collagen synthesis, and iron absorption. |
75 mg | |
|
Vitamin B6 (as pyridoxal-5'-phosphate and pyridoxine hydrochloride)
Vitamin B6
Vitamin B6 supports amino acid metabolism, cognitive development, and immune function. |
85 mg | |
|
Folate (as 400 mcg (6S)-5-methyltetrahydrofolic acid, glucosamine salt)†
Folate
Folate is a B vitamin important for DNA synthesis, cell division, and prenatal development. It supports cardiovascular and neurological health. |
680 mcg DFE | |
|
Pantothenic Acid (as d-calcium pantothenate)
Pantothenic Acid
Pantothenic Acid (Vitamin B5) supports adrenal function, energy metabolism, and synthesis of coenzyme A. |
750 mg | |
|
Acetyl L-Carnitine (as Acetyl L-Carnitine hydrochloride)
Acetyl L-Carnitine
Acetyl L-Carnitine is a form of carnitine that crosses the blood-brain barrier and supports cognitive function, energy metabolism, and mitochondrial health. |
150 mg | |
|
Citrus Bioflavonoid Complex (Citrus spp.) (peel) extract (NLT 50% Bioflavonoids)
Citrus Bioflavonoid Complex
Citrus Bioflavonoid Complex is a blend of plant compounds that support capillary strength, antioxidant activity, and enhance vitamin C absorption. |
75 mg | |
|
Black Pepper (Piper nigrum) (fruit) extract††
Black Pepper
Black Pepper contains piperine, which supports digestive health and enhances nutrient absorption by increasing gastrointestinal activity. |
2 mg | |
| 1 The % Daily Value tells you how much a nutrient in a serving of food contributes to a daily diet. 2,000 calories a day is used for general nutrition advise. | ||
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Corti-B Plex is commonly used when stress feels physically draining rather than just mentally busy. This can include periods of prolonged pressure where stamina, recovery, or steady energy becomes harder to maintain. The formula focuses on nutrients often associated with adrenal hormone production rather than broad daily coverage.
General B-complex formulas are designed to provide balanced, everyday coverage across all B vitamins. Corti-B Plex narrows that focus, emphasizing higher amounts of specific B vitamins commonly involved in stress response and energy metabolism. This difference matters most when overall stress demands increase.
Corti-B Plex is often used during periods of increased stress rather than as a permanent daily foundation. Some people use it temporarily and later return to a general B-complex once demands ease. Others continue it longer when stress patterns remain consistent.
No. Corti-B Plex relies on vitamins and related nutrients rather than adaptogenic herbs. This makes it a consideration for individuals who want adrenal-focused nutritional support without introducing botanical ingredients.
Corti-B Plex focuses on targeted B vitamins and supportive nutrients, while adrenal formulas such as AdrenaMed include adaptogenic herbs in addition to vitamins. Corti-B Plex is often considered earlier, before stress patterns suggest the need for a broader adrenal strategy.
Individuals looking for general, everyday B-vitamin support may prefer a full B-complex. Those dealing with more persistent or complex stress patterns may later consider formulas that include adaptogenic herbs. Corti-B Plex fits between these approaches rather than replacing either one.
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